
Why do some women barely experience morning sickness while others feel sick all day during pregnancy?
If you’ve ever wondered what causes morning sickness, you’re not alone. For years, experts believed morning sickness was simply due to pregnancy hormones. But new research is changing what we know about pregnancy nausea causes.
Morning sickness during pregnancy affects up to 80% of pregnant women, especially during the first trimester. Although it’s called “morning” sickness, nausea can happen at any time of the day.
Symptoms range from mild nausea to severe vomiting that may require medical treatment.
What Really Causes Morning Sickness in Pregnancy?
New studies point to a hormone called GDF15 (Growth Differentiation Factor 15) as a major factor behind the causes of nausea in early pregnancy.
Produced by the placenta and your growing baby, GDF15 communicates with the part of the brain that controls nausea and vomiting. During pregnancy, its levels rise dramatically, helping support placental development and protect early pregnancy.
For decades, researchers proposed several possible morning sickness causes, including:
- Rising hCG (human chorionic gonadotropin) levels
- Increased estrogen
- Heightened sense of smell
- Evolutionary protection against harmful foods
- Changes in digestion

These ideas explained parts of the puzzle but never fully answered what causes morning sickness for every pregnant woman.
Why Are Some Women More Sick Than Others?
The latest research suggests it’s not just the amount of GDF15 that matters—it’s how sensitive your body is to it. Although GDF15 is linked to nausea, it also serves important functions.
Researchers believe it helps:
- Support early pregnancy
- Promote healthy placental development
- Protect the pregnancy during times of stress
- Help the body respond to potential toxins

In other words, your body isn’t malfunctioning.
It’s responding to signals that help support a healthy pregnancy.
This breakthrough helps explain what really causes morning sickness in pregnancy and why every pregnancy feels different.
What Does This Mean for You?
Understanding the science behind morning sickness shows that your body isn’t failing. It’s responding to important pregnancy signals in its own way.
While there is no proven way to change your body’s sensitivity to GDF15, treatments such as dietary changes, vitamin B6, ginger, prescribed medications, and hydration may help relieve symptoms. Always speak with your healthcare provider if nausea becomes severe or you cannot keep fluids down.
New Research Explains Morning Sickness
Recent studies suggest that women with severe morning sickness often have lower GDF15 levels before pregnancy. Once pregnancy begins, this hormone rises rapidly, and women who are more sensitive to it may experience stronger nausea. This discovery helps explain what really causes morning sickness in pregnancy and shows that your body is responding differently, not failing. If you’ve been wondering why you feel sick during pregnancy, this new understanding can offer reassurance.
What This Means for the Future
Researchers are still studying whether the body’s sensitivity to GDF15 can be changed. For now, treatments focus on easing symptoms with hydration, nutrition, vitamin B6, ginger, medications, and other supportive care. The discovery of GDF15 has transformed the science behind morning sickness and improved our understanding of what causes morning sickness, giving hope for better treatments in the future.
The newest research is reshaping our understanding of morning sickness during pregnancy. Instead of blaming “just hormones,” scientists now believe GDF15 and your body’s response to it play a key role in pregnancy nausea causes.
Knowing what causes morning sickness can help reassure you that your symptoms are part of a complex biological process, and that you’re not alone.
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